| 2. | st 12.08.202012.08. | ŠKF ORION TIP SereďSER | 4:0 |  FK SenicaSEN | 28 | 1 | 0 | 20,0% | 83,3% | 6 | 0 |
| 3. | so 15.08.202015.08. | MFK RužomberokRUŽ | 0:0 | ŠKF ORION TIP SereďSER | 36 | 0 | 0 | 38,5% | 53,3% | 15 | 0 |
| 5. | so 29.08.202029.08. | FC Spartak TrnavaSPA | 0:2 | ŠKF ORION TIP SereďSER | 82 | 1 | 0 | 52,6% | 70,0% | 20 | 0 |
| 6. | so 12.09.202012.09. | ŠKF ORION TIP SereďSER | 3:2 |  MŠK ŽilinaMŠK | 76 | 0 | 1 | 57,1% | 77,3% | 22 | 0 |
| 7. | so 19.09.202019.09. | FK Pohronie Žiar n.H. Dolná ŽdaňaPOH | 2:2 | ŠKF ORION TIP SereďSER | 89 | 0 | 0 | 37,0% | 64,7% | 17 | 0 |
| 4. | ut 22.09.202022.09. | ŠKF ORION TIP SereďSER | 1:1 |  AS TrenčínTRE | 74 | 0 | 0 | 27,8% | 60,0% | 20 | 0 |
| 8. | so 26.09.202026.09. | FC NitraNIT | 3:0 | ŠKF ORION TIP SereďSER | 76 | 0 | 0 | 42,9% | 63,9% | 36 | 0 |
| 9. | so 03.10.202003.10. | ŠKF ORION TIP SereďSER | 1:1 |  MFK Zemplín MichalovceMIC | 90 | 0 | 0 | 35,3% | 85,4% | 41 | 0 |
| 10. | so 17.10.202017.10. | ŠK Slovan Bratislava SLO | 3:0 | ŠKF ORION TIP SereďSER | 82 | 0 | 0 | 38,1% | 76,9% | 26 | 0 |
| 11. | so 24.10.202024.10. | ŠKF ORION TIP SereďSER | 1:2 |  FC ViOn Zlaté Moravce - VrábleZMO | 57 | 0 | 0 | 46,2% | 57,9% | 19 | 0 |
| 13. | ut 17.11.202017.11. | FK SenicaSEN | 2:2 | ŠKF ORION TIP SereďSER | 83 | 0 | 0 | 45,5% | 80,0% | 25 | 0 |
| 14. | so 21.11.202021.11. | ŠKF ORION TIP SereďSER | 0:0 | MFK RužomberokRUŽ | 34 | 0 | 0 | 33,3% | 75,0% | 8 | 0 |
| 15. | ne 29.11.202029.11. | AS TrenčínTRE | 1:0 | ŠKF ORION TIP SereďSER | 87 | 0 | 0 | 52,4% | 59,1% | 22 | 0 |
| 12. | st 02.12.202002.12. | ŠKF ORION TIP SereďSER | 1:0 |  FC DAC 1904 Dunajská StredaDAC | 90 | 0 | 0 | 25,0% | 59,1% | 22 | |
| 16. | so 05.12.202005.12. | ŠKF ORION TIP SereďSER | 2:6 | FC Spartak TrnavaSPA | 90 | 0 | 1 | 35,0% | 74,1% | 27 | 0 |
| 17. | so 12.12.202012.12. | MŠK ŽilinaMŠK | 0:0 | ŠKF ORION TIP SereďSER | 86 | 0 | 0 | 41,2% | 75,9% | 29 | |
| 18. | ut 09.02.202109.02. | ŠKF ORION TIP SereďSER | 0:2 | FK Pohronie Žiar n.H. Dolná ŽdaňaPOH | 64 | 0 | 0 | 53,8% | 50,0% | 26 | 0 |
| 22. | so 06.03.202106.03. | FC ViOn Zlaté Moravce - VrábleZMO | 1:0 | ŠKF ORION TIP SereďSER | 70 | 0 | 0 | 36,4% | 75,0% | 16 | 0 |
| Z - 1. | so 13.03.202113.03. | ŠKF ORION TIP SereďSER | 1:0 | MFK RužomberokRUŽ | 64 | 0 | 1 | 37,5% | 58,1% | 31 | 0 |
| Z - 2. | so 20.03.202120.03. | FK SenicaSEN | 1:0 | ŠKF ORION TIP SereďSER | 71 | 0 | 0 | 25,0% | 65,0% | 20 | 0 |
| Z - 3. | so 03.04.202103.04. | FK Pohronie Žiar n.H. Dolná ŽdaňaPOH | 1:2 | ŠKF ORION TIP SereďSER | 3 | 0 | 0 | 0,0% | 0,0% | 0 | 0 |
| Z - 4. | so 10.04.202110.04. | ŠKF ORION TIP SereďSER | 2:1 | FC NitraNIT | 44 | 0 | 0 | 7,7% | 83,3% | 12 | 0 |
| Z - 5. | so 17.04.202117.04. | ŠKF ORION TIP SereďSER | 2:0 | MFK Zemplín MichalovceMIC | 55 | 0 | 0 | 28,6% | 80,0% | 10 | |
| Z - 6. | so 24.04.202124.04. | MFK RužomberokRUŽ | 2:1 | ŠKF ORION TIP SereďSER | 60 | 0 | 0 | 8,3% | 71,4% | 7 | |
| Z - 8. | ne 09.05.202109.05. | FC NitraNIT | 0:1 | ŠKF ORION TIP SereďSER | 14 | 0 | 0 | 20,0% | 80,0% | 5 | |
| Z - 10. | so 22.05.202122.05. | ŠKF ORION TIP SereďSER | 4:1 | FK SenicaSEN | 70 | 1 | 1 | 48,3% | 88,9% | 18 | 0 |
| - 1. | ut 25.05.202125.05. | MŠK ŽilinaMŠK | 4:2 | ŠKF ORION TIP SereďSER | 90 | 1 | 0 | 0,0% | 0,0% | 0 | 0 |
