| 1. | so 08.08.202008.08. | MFK Zemplín MichalovceMIC | 0:2 |  FC Spartak TrnavaSPA | 90 | 0 | 0 | 58,8% | 64,9% | 74 | 0 |
| 2. | ut 11.08.202011.08. | ŠK Slovan Bratislava SLO | 5:0 | MFK Zemplín MichalovceMIC | 90 | 0 | 0 | 66,7% | 73,0% | 37 | 0 |
| 3. | so 15.08.202015.08. | FK SenicaSEN | 3:0 | MFK Zemplín MichalovceMIC | 11 | 0 | 0 | 0,0% | 50,0% | 4 | 0 |
| 4. | ut 25.08.202025.08. | MFK Zemplín MichalovceMIC | 1:0 |  FC ViOn Zlaté Moravce - VrábleZMO | 90 | 0 | 0 | 66,7% | 62,3% | 61 | 0 |
| 5. | ne 30.08.202030.08. | MŠK ŽilinaMŠK | 6:2 | MFK Zemplín MichalovceMIC | 90 | 0 | 0 | 33,3% | 78,0% | 50 | |
| 8. | so 26.09.202026.09. | MFK Zemplín MichalovceMIC | 2:0 |  FK Pohronie Žiar n.H. Dolná ŽdaňaPOH | 90 | 0 | 0 | 57,1% | 59,5% | 42 | 0 |
| 11. | so 24.10.202024.10. | FC NitraNIT | 1:1 | MFK Zemplín MichalovceMIC | 90 | 0 | 0 | 40,0% | 60,4% | 48 | 0 |
| 12. | so 31.10.202031.10. | FC Spartak TrnavaSPA | 1:2 | MFK Zemplín MichalovceMIC | 90 | 0 | 0 | 50,0% | 63,3% | 30 | 0 |
| 13. | so 07.11.202007.11. | MFK Zemplín MichalovceMIC | 0:2 | ŠK Slovan Bratislava SLO | 90 | 0 | 0 | 58,3% | 59,0% | 39 | |
| 14. | so 21.11.202021.11. | MFK Zemplín MichalovceMIC | 0:1 | FK SenicaSEN | 90 | 0 | 0 | 66,7% | 69,0% | 58 | 0 |
| 15. | so 28.11.202028.11. | FC ViOn Zlaté Moravce - VrábleZMO | 0:0 | MFK Zemplín MichalovceMIC | 90 | 0 | 0 | 42,9% | 60,7% | 56 | |
| 16. | so 05.12.202005.12. | MFK Zemplín MichalovceMIC | 1:1 | MŠK ŽilinaMŠK | 90 | 0 | 0 | 45,5% | 72,9% | 59 | 0 |
| 17. | ne 13.12.202013.12. | AS TrenčínTRE | 2:2 | MFK Zemplín MichalovceMIC | 90 | 0 | 1 | 63,6% | 61,2% | 49 | 0 |
| 18. | st 16.12.202016.12. | MFK Zemplín MichalovceMIC | 4:3 |  MFK RužomberokRUŽ | 90 | 0 | 0 | 55,6% | 56,5% | 46 | 0 |
| 20. | so 20.02.202120.02. | MFK Zemplín MichalovceMIC | 0:2 |  ŠKF ORION TIP SereďSER | 90 | 0 | 0 | 27,3% | 66,7% | 39 | 0 |
| 21. | so 27.02.202127.02. | FC DAC 1904 Dunajská StredaDAC | 2:1 | MFK Zemplín MichalovceMIC | 90 | 0 | 0 | 57,1% | 57,1% | 35 | 0 |
| 22. | so 06.03.202106.03. | MFK Zemplín MichalovceMIC | 1:0 | FC NitraNIT | 90 | 0 | 0 | 42,1% | 62,7% | 75 | 0 |
| Z - 1. | so 13.03.202113.03. | MFK Zemplín MichalovceMIC | 1:1 | FC NitraNIT | 90 | 0 | 0 | 75,0% | 69,0% | 58 | 0 |
| Z - 2. | so 20.03.202120.03. | MFK RužomberokRUŽ | 2:0 | MFK Zemplín MichalovceMIC | 90 | 0 | 0 | 54,5% | 74,6% | 63 | 0 |
| Z - 3. | so 03.04.202103.04. | MFK Zemplín MichalovceMIC | 1:0 | FK SenicaSEN | 90 | 0 | 0 | 55,6% | 45,8% | 48 | 0 |
| Z - 4. | so 10.04.202110.04. | MFK Zemplín MichalovceMIC | 1:2 | FK Pohronie Žiar n.H. Dolná ŽdaňaPOH | 84 | 0 | 0 | 40,0% | 54,3% | 46 | 0 |
| Z - 8. | so 08.05.202108.05. | FK Pohronie Žiar n.H. Dolná ŽdaňaPOH | 0:0 | MFK Zemplín MichalovceMIC | 90 | 0 | 0 | 56,3% | 68,7% | 67 | |
| Z - 9. | so 15.05.202115.05. | MFK Zemplín MichalovceMIC | 2:2 | ŠKF ORION TIP SereďSER | 33 | 0 | 0 | 62,5% | 66,7% | 27 | 0 |
